Pulsed Nd:YAG 레이저로 유발된 백서 설점막 창상의 조직학적 변화
Histological Changes of the Wound in the Tongue Mucosa of White
박준상, 박봉수, 박미희,
소속 상세정보
박준상 ( ) - 부산대학교 치과대학 구강내과학교실
박봉수 ( ) - 구강해부학교실
박미희 ( ) - 부산대학교 치과대학 구강내과학교실
KMID : 0355219970220010125
Abstract
The Author examined the clinical and histological changes on the dorsal tongue mucosa of the adult rats after lasing by pulsed Nd:YAG laser and incising with scalpel. The dorsal tongue was lased through 320pe-optic fiber moving 2.5mmlsecond to make linear incsion 5mm. The five conditions of lasing were three applications with 1.0W, L75W, 3.0W and 3.0W under saline cooling, and single application with 3.0W at 20 Hz. With scalpel, linear incisions through the surface epithelium were performed to 5rnm in length. After observing the clinical changes of the incised wounds: the animals were sacrified and the tissues were excised, to make the tissue specimens. The stained microscopic tissue slides were observed histologically under the microscope.
The following results were obtained:
1. While incision with scalpel causes severe bleeding, lasing does not cause bleeding.
2. In three applications with 1.75W and MHz, tissue ablation was limited to areas contacted with optic fiber. 3. In three applications with 3.0W and MHz, deep incised wound, extensive destruction of the adjacent epithelium
and charring were observed.
4. In three applications with 3.0W and 20Hz under saline cooling, tissue ablation was limited to the superficial tnucosa and charring was not observed.
5. In single application with 3.0W and 20Hz, the shape of the incised wound was similar to that of the scalpel incision.
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